• Adipokines and inflammation markers and risk of differentiated thyroid carcinoma: The EPIC study 

      Dossus, Laure; Franceschi, Silvia; Biessy, Carine; Navionis, Anne-Sophie; Travis, Ruth C.; Weiderpass, Elisabete; Scalbert, Augustin; Romieu, Isabelle; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Boutron-Ruault, Marie-Christine; Bonnet, Fabrice; Fournier, Agnès; Fortner, Renée Turzanski; Kaaks, Rudolf; Aleksandrova, Krasimira; Trichopoulou, Antonia; La Vecchia, Carlo; Peppa, Eleni; Tumino, Rosario; Panico, Salavatore; Palli, Domenico; Agnoli, Claudia; Vineis, Paolo; Bueno-de-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Skeie, Guri; Zamora-Ros, Raul; Chirlaque, María-Dolores; Ardanaz, Eva; Sánchez, Maria-Jose; Quirós, Jose Ramón; Dorronsoro, Miren; Sandström, Maria; Nilsson, Lena Maria; Schmidt, Julie A.; Khaw, Kay-Tee; Tsilidis, Konstantinos K.; Aune, Dagfinn; Riboli, Elio; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-23)
      Other than the influence of ionizing radiation and benign thyroid disease, little is known about the risk factors for differentiated thyroid cancer (TC) which is an increasing common cancer worldwide. Consistent evidence shows that body mass is positively associated with TC risk. As excess weight is a state of chronic inflammation, we investigated the relationship between concentrations of leptin, ...
    • Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study 

      Ritte, Rebecca; Lukanova, Annekatrin; Berrino, Franco; Dossus, Laure; Tjønneland, Anne; Olsen, Anja; Overvad, Thure F.; Overvad, Kim; Clavel-Chapelon, Françoise; Fournier, Agnes; Fagherazzi, Guy; Rohrmann, Sabine; Teucher, Birgit; Boeing, Heiner; Aleksandrova, Krasimira; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Quiros, Jose R; Buckland, Genevieve; Sanchez, Maria-José; Amiano, Pilar; Chirlaque, María Dolores; Ardanaz, Eva; Sund, Malin; Lenner, Per; Bueno-de-Mesquita, Bas; van Gils, Carla H.; Peeters, Petra H.M.; Krum-Hansen, Sanda; Gram, Inger Torhild; Lund, Eiliv; Khaw, Kay-Tee; Wareham, Nick; Allen, Naomi E.; Key, Timothy J.; Romieu, Isabelle; Rinaldi, Sabina; Siddiq, Afshan; Cox, David; Riboli, Elio; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-05-14)
      Introduction: Associations of hormone-receptor positive breast cancer with excess adiposity are reasonably well characterized; however, uncertainty remains regarding the association of body mass index (BMI) with hormonereceptor negative malignancies, and possible interactions by hormone replacement therapy (HRT) use. Methods: Within the European EPIC cohort, Cox proportional hazards models were used ...
    • Alcohol intake and breast cancer in the European prospective investigation into cancer and nutrition 

      Romieu, Isabelle; Scoccianti, Chiara; Chajès, Véronique; De Batlle, Jordi; Biessy, Carine; Dossus, Laure; Baglietto, Laura; Clavel-Chapelon, Françoise; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Lukanova, Annekatrin; Boeing, Heiner; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; van Gils, Carla H.; Peeters, Petra H.; Lund, Eiliv; Skeie, Guri; Weiderpass, Elisabete; García, José Ramón Quirós; Chirlaque, Maria-Dolores; Ardanaz, Eva; Sánchez, María-José; Duell, Eric J.; Amiano, Pilar; Borgquist, Signe; Wirfält, Elisabet; Hallmans, Göran; Johansson, Ingegerd; Nilsson, Lena Maria; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Travis, Ruth C.; Murphy, Neil; Wark, Petra A.; Ferrari, Pietro; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-09)
      Alcohol intake has been associated to breast cancer in pre and postmenopausal women; however results are inconclusive regarding tumor hormonal receptor status, and potential modifying factors like age at start drinking. Therefore, we investigated the relation between alcohol intake and the risk of breast cancer using prospective observational data from the European Prospective Investigation into ...
    • Anti-cancer therapy is associated with long-term epigenomic changes in childhood cancer survivors 

      Robinson, Natassia; Casement, John; Gunter, Marc J.; Huybrechts, Inge; Agudo, Antonio; Barranco, Miguel Rodríguez; Eichelmann, Fabian; Johnson, Theron; Kaaks, Rudolf; Pala, Valeria; Panico, Salvatore; Sandanger, Torkjel M; Schultze, Matthias B.; Travis, Ruth C.; Tumino, Rosario; Vineis, Paolo; Weiderpass, Elisabete; Skinner, Roderick; Sharp, Linda; McKay, Jill A; Strathdee, Gordon (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-30)
      BACKGROUND: Childhood cancer survivors (CCS) exhibit significantly increased chronic diseases and premature death. Abnormalities in DNA methylation are associated with development of chronic diseases and reduced life expectancy. We investigated the hypothesis that anti-cancer treatments are associated with long-term DNA methylation changes that could be key drivers of adverse late health ...
    • Appraising the causal relevance of DNA methylation for risk of lung cancer 

      Battram, Thomas; Richmond, Rebecca C.; Baglietto, Laura; Haycock, Philip C.; Perduca, Vittorio; Bojesen, Stig E.; Gaunt, Tom R.; Hemani, Gibran; Guida, Florence; Carreras-Torres, Robert; Hung, Rayjean; Amos, Christopher I.; Freeman, Joshua R.; Sandanger, Torkjel M; Nøst, Therese Haugdahl; Nordestgaard, Børge G.; Teschendorff, Andrew E.; Polidoro, Silvia; Vineis, Paolo; Severi, Gianluca; Hodge, Allison M.; Giles, Graham G; Grankvist, Kjell; Johansson, Mikael B.; Johansson, Mattias; Smith, George Davey; Relton, Caroline L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-24)
      <i>Background</i> - DNA methylation changes in peripheral blood have recently been identified in relation to lung cancer risk. Some of these changes have been suggested to mediate part of the effect of smoking on lung cancer. However, limitations with conventional mediation analyses mean that the causal nature of these methylation changes has yet to be fully elucidated.<p> <p><i>Methods</i> - We ...
    • Assessment of the EarlyCDT-Lung test as an early biomarker of lung cancer in ever-smokers: A retrospective nested case-control study in two prospective cohorts 

      Wu, Wendy Yi-Ying; Haider, Zahra; Feng, Xiaoshuang; Heath, Alicia K.; Tjønneland, Anne; Agudo, Antonio; Masala, Giovanna; Robbins, Hilary A.; Huerta, María-José; Guevara, Marcela; Schulze, Matthias B.; Rodriguez-Barranco, Miguel; Vineis, Paolo; Tumino, Rosario; Kaaks, Rudolf; Fortner, Renée T.; Sieri, Sabina; Panico, Salvatore; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Braaten, Tonje; Johansson, Mattias; Melin, Beatrice; Johansson, Mikael (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-28)
      The EarlyCDT-Lung test is a blood-based autoantibody assay intended to identify high-risk individuals for low-dose computed tomography lung cancer screening. However, there is a paucity of evidence on the performance of the EarlyCDT-Lung test in ever-smokers. We conducted a nested case-control study within two prospective cohorts to evaluate the risk-discriminatory performance of the EarlyCDT-Lung ...
    • The association of education with body mass index and waist circumference in the EPIC-PANACEA study 

      Hermann, Silke; Rohrmann, Sabine; Linseisen, Jakob; May, Anne M.; Kunst, Anton; Besson, Herve; Romaguera, Dora; Travier, Noemie; Tormo, Maria-José; Molina, Esther; Dorronsoro, Miren; Barricarte, Aurelio; Rodriguez, Laudina; Crowe, Francesca L.; Khaw, Kay-Tee; Wareham, Nicholas J.; van Boeckel, Petra G.A.; Bueno-de-Mesquita, H. Bas; Overvad, Kim; Jakobsen, Marianne Uhre; Tjønneland, Anne; Halkjær, Jytte; Agnoli, Claudia; Mattiello, Amalia; Tumino, Rosario; Masala, Giovanna; Vineis, Paolo; Naska, Androniki; Orfanos, Philippos; Trichopoulou, Antonia; Kaaks, Rudolf; Bergmann, Manuela M.; Steffen, Annika; Van Guelpen, Bethany; Johansson, Ingegerd; Borgquist, Signe; Manjer, Jonas; Braaten, Tonje; Fagherazzi, Guy; Clavel-Chapelon, Françoise; Mouw, Traci; Norat, Teresa; Riboli, Elio; Rinaldi, Sabina; Slimani, Nadia; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      To examine the association of education with body mass index (BMI) and waist circumference (WC) in the European Prospective Investigation into Cancer and Nutrition (EPIC). This study included 141,230 male and 336,637 female EPIC-participants, who were recruited between 1992 and 2000. Education, which was assessed by questionnaire, was classified into four categories; BMI and WC, measured by trained ...
    • Baseline and lifetime alcohol consumption and risk of differentiated thyroid carcinoma in the EPIC study 

      Sen, Abhijit; Tsilidis, Konstantinos K.; Allen, Naomi E.; Rinaldi, Sabina; Appleby, Paul N.; Almquist, Martin; Schmidt, Julie A.; Dahm, Christina C.; Overvad, Kim; Tjønneland, Anne; Rostgaard-Hansen, Agnetha L.; Clavel-Chapelon, Françoise; Baglietto, Laura; Boutron-Ruault, Marie-Christine; Kühn, Tilman; Katze, Verena A.; Boeing, Heiner; Trichopoulou, Antonia; Tsironis, Christos; Lagiou, Pagona; Palli, Domenico; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Hjartåker, Anette; Lund, Eiliv; Weiderpass, Elisabete; Quirós, J. Ramón; Agudo, Antonio; Sánchez, Mariá-José; Arriola, Larraitz; Gavrila, Diana; Gurrea, Aurelio Barricarte; Tosovic, Ada; Hennings, Joakim; Sandström, Maria; Romieu, Isabelle; Ferrari, Pietro; Zamora-Ros, Raul; Khaw, Kay-Tee; Wareham, Nicholas J.; Riboli, Elio; Gunter, Marc; Franceschi, Silvia (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-27)
      Background: Results from several cohort and case–control studies suggest a protective association between current alcohol intake and risk of thyroid carcinoma, but the epidemiological evidence is not completely consistent and several questions remain unanswered.<p> <p>Methods: The association between alcohol consumption at recruitment and over the lifetime and risk of differentiated thyroid carcinoma ...
    • Blood cell DNA methylation biomarkers in preclinical malignant pleural mesothelioma: The EPIC prospective cohort 

      Allione, Alessandra; Viberti, Clara; Cotellessa, Ilaria; Catalano, Chiara; Casalone, Elisabetta; Cugliari, Giovanni; Russo, Alessia; Guarrera, Simonetta; Mirabelli, Dario; Sacerdote, Carlotta; Gentile, Marco; Eichelmann, Fabian; Schulze, Matthias B.; Harlid, Sophia; Eriksen, Anne Kirstine; Tjønneland, Anne; Andersson, Martin; Dollé, Martijn E.T.; Van Puyvelde, Heleen; Weiderpass, Elisabete; Rodriguez-Barranco, Miguel; Agudo, Antonio; Heath, Alicia K.; Chirlaque, María-Dolores; Truong, Thérèse; Dragic, Dzevka; Severi, Gianluca; Sieri, Sabina; Sandanger, Torkjel M; Ardanaz, Eva; Vineis, Paolo; Matullo, Giuseppe (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-28)
      Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer mainly caused by asbestos exposure. Specific and sensitive noninvasive biomarkers may facilitate and enhance screening programs for the early detection of cancer. We investigated DNA methylation (DNAm) profiles in MPM prediagnostic blood samples in a case-control study nested in the European Prospective Investigation into Cancer ...
    • Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts 

      Rothwell, Joseph A.; Bešević, Jelena; Dimou, Niki; Breeur, Marie; Murphy, Neil; Jenab, Mazda; Wedekind, Roland; Viallon, Vivian; Ferrari, Pietro; Achaintre, David; Gicquiau, Audrey; Rinaldi, Sabina; Scalbert, Augustin; Huybrechts, Inge; Prehn, Cornelia; Adamski, Jerzy; Cross, Amanda J.; Keun, Hector; Chadeau-Hyam, Marc; Boutron-Ruault, Marie-Christine; Overvad, Kim; Dahm, Christina C.; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Skeie, Guri; Zamora-Ros, Raul; Tsilidis, Kostas K.; Eichelmann, Fabian; Schulze, Matthias B.; van Guelpen, Bethany; Vidman, Linda; Sánchez, Maria-José; Amiano, Pilar; Ardanaz, Eva; Smith-Byrne, Karl; Travis, Ruth; Katzke, Verena; Kaaks, Rudolf; Derksen, Jeroen W. G.; Colorado-Yohar, Sandra; Tumino, Rosario; Bueno-de-Mesquita, Bas; Vineis, Paolo; Palli, Domenico; Pasanisi, Fabrizio; Eriksen, Anne Kirstine; Tjønneland, Anne; Severi, Gianluca; Gunter, Marc J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-28)
      Background Amino acid metabolism is dysregulated in colorectal cancer patients; however, it is not clear whether pre-diagnostic levels of amino acids are associated with subsequent risk of colorectal cancer. We investigated circulat‑ ing levels of amino acids in relation to colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) and UK Biobank ...
    • Circulating biomarkers of one-carbon metabolism in relation to renal cell carcinoma incidence and survival 

      Johansson, Mattias; Anouar, Fanidi; Muller, David C.; Bassett, Julie K.; Midttun, Øivind; Vollset, Stein Emil; Travis, Ruth C.; Palli, Domenico; Mattiello, Amalia; Sieri, Sabina; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Ljungberg, Börje; Hallmans, Göran; Weiderpass, Elisabete; Skeie, Guri; Gonzalez, Carlos A.; Dorronsoro, Miren; Peeters, Petra H.; Bueno-de-Mesquita, H. B(as).; Ros, Martine M.; Ruault, Marie-Christine Boutron; Fagherazzi, Guy; Clavel, Françoise; Sanchez, Maria-Jose; Gurrea, Aurelio Barricarte; Navarro, Carmen; Quirós, J. Ramón; Overvad, Kim; Tjønneland, Anne; Aleksandrova, Krassimira; Vineis, Paolo; Gunter, Marc J.; Kaaks, Rudolf; Giles, Graham; Relton, Caroline; Riboli, Elio; Boeing, Heiner; Ueland, Per Magne; Severi, Gianluca; Brennan, Paul (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-11-05)
      The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival. Methods The European Prospective Investigation into Cancer and Nutrition (EPIC) recruited 385747 participants with blood samples between 1992 and 2000, and this analysis included 556 RCC case-control pairs. ...
    • Circulating Isovalerylcarnitine and Lung Cancer Risk: Evidence from Mendelian Randomization and Prediagnostic Blood Measurements 

      Smith-Byrne, Karl; Cerani, Agustin; Guida, Florence; Zhou, Sirui; Agudo, Antonio; Aleksandrova, Krasimira; Barricarte, Aurelio; Barranco, Miguel Rodríguez; Bochers, Christoph H.; Gram, Inger Torhild; Han, Jun; Amos, Christopher I.; Hung, Rayjean J.; Grankvist, Kjell; Nøst, Therese Haugdahl; Imaz, Liher; Chirlaque-López, María Dolores; Johansson, Mikael; Kaaks, Rudolf; Kühn, Tilman; Martin, Richard M.; McKay, James D.; Pala, Valeria; Robbins, Hilary A.; Sandanger, Torkjel M; Schibli, David; Schulze, Matthias B.; Travis, Ruth C.; Vineis, Paolo; Weiderpass, Elisabete; Brennan, Paul; Johansson, Mattias; Richards, J Brent (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-04)
      Background: Tobacco exposure causes 8 of 10 lung cancers, and identifying additional risk factors is challenging due to confounding introduced by smoking in traditional observational studies.<p> <p>Materials and Methods: We used Mendelian randomization (MR) to screen 207 metabolites for their role in lung cancer predisposition using independent genome-wide association studies (GWAS) of blood ...
    • Circulating Vitamin D in relation to cancer incidence and survival of the head and neck and oesophagus in the EPIC cohort 

      Fanidi, Anouar; Muller, David C.; Midttun, Øivind; Ueland, Per Magne; Vollset, Stein Emil; Relton, Caroline; Vineis, Paolo; Weiderpass, Elisabete; Skeie, Guri; Brustad, Magritt; Palli, Domenico; Tumino, Rosario; Grioni, Sara; Sacerdote, Carlotta; Bueno-de-Mesquita, H. Bas; Peeters, Petra H.; Boutron-Ruault, Marie-Christine; Kvaskoff, Marina; Cadeau, Claire; Huerta, José María; Sánchez, María-José; Agudo, Antonio; Lasheras, Cristina; Quirós, J. Ramón; Chamosa, Saioa; Riboli, Elio; Travis, Ruth C; Ward, Heather; Murphy, Neil; Khaw, Kay-Tee; Trichopoulou, Antonia; Lagiou, Pagona; Papatesta, Eleni-Maria; Boeing, Heiner; Kühn, Tilman; Katzke, Verena; Steffen, Annika; Johansson, Anders; Brennan, Paul; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-04)
      Experimental and epidemiological data suggest that vitamin D play a role in pathogenesis and progression of cancer, but prospective data on head and neck cancer (HNC) and oesophagus cancer are limited. The European Prospective Investigation into Cancer and Nutrition (EPIC) study recruited 385,747 participants with blood samples between 1992 and 2000. This analysis includes 497 case-control pairs ...
    • Co-benefits from sustainable dietary shifts for population and environmental health: an assessment from a large European cohort study 

      Laine, Jessica E; Huybrechts, Inge; Gunter, Marc J; Ferrari, Pietro; Weiderpass, Elisabete; Tsilidis, Kostas; Aune, Dagfinn; Schulze, Matthias B; Bergmann, Manuela; Boer, Jolanda M A; Agnoli, Claudia; Ericson, Ulrika; Stubbendorff, Anna; Ibsen, Daniel B; Dahm, Christina Catherine; Deschasaux, Mélanie; Touvier, Mathilde; Kesse-Guyot, Emmanuelle; Sánchez Pérez, Maria-Jose; Rodríguez Barranco, Miguel; Tong, Tammy Y N; Papier, Keren; Knuppel, Anika; Boutron-Ruault, Marie-Christine; Mancini, Francesca; Severi, Gianluca; Srour, Bernard; Kühn, Tilman; Masala, Giovanna; Agudo, Antonio; Skeie, Guri; Rylander, Charlotta; Sandanger, Torkjel M; Vineis, Paolo (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-22)
      Background - Unhealthy diets, the rise of non-communicable diseases, and the declining health of the planet are highly intertwined, where food production and consumption are major drivers of increases in greenhouse gas emissions, substantial land use, and adverse health such as cancer and mortality. To assess the potential co-benefits from shifting to more sustainable diets, we aimed to investigate ...
    • Combined Impact of Lifestyle Factors on Prospective Change in Body Weight and Waist Circumference in Participants of the EPIC-PANACEA Study 

      May, Anne M.; Romaguera, Dora; Travier, Noémie; Ekelund, Ulf; Bergmann, Manuela M.; Kaaks, Rudolf; Teucher, Birgit; Steffen, Annika; Boeing, Heiner; Halkjaer, Jytte; Tjonneland, Anne; Jakobsen, Marianne Uhre; Overvad, Kim; Dartois, Laureen; Fagherazzi, Guy; Boutron-Ruault, Marie-Christine; Quirós, J. Ramón; Agudo, Antonio; Gonzalez, Carlos; Sanchez, Maria-José; Amiano, Pilar; Huerta, José-Maria; Ardanaz, Eva; Wareham, Nicholas J.; Crowe, Francesca L.; Naska, Androniki; Orfanos, Philippos; Trichopoulou, Antonia; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Bueno-de-Mesquita, H. Bas; Verschuren, Monique; Drake, Isabel; Sonestedt, Emily; Braaten, Tonje; Rinaldi, Sabina; Romieu, Isabelle; Slimani, Nadia; Norat, Teresa; Riboli, Eilo; Peeters, Petra H.M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The evidence that individual dietary and lifestyle factors influence a person’s weight and waist circumference is well established; however their combined impact is less well documented. Therefore, we investigated the combined effect of physical activity, nutrition and smoking status on prospective gain in body weight and waist circumference. We used data of the prospective EPIC-PANACEA study. ...
    • Comparison of prognostic models to predict the occurrence of colorectal cancer in asymptomatic individuals: A systematic literature review and external validation in the EPIC and UK Biobank prospective cohort studies 

      Smith, Todd; Muller, David C.; Moons, Karel G.M.; Cross, Amanda J.; Johansson, Mattias; Ferrari, Pietro; Fagherazzi, Guy; Peeters, Petra H. M.; Severi, Gianluca; Hüsing, Anika; Kaaks, Rudolf; Tjønneland, Anne; Olsen, Anja; Overvad, Kim; Bonet, Catalina; Rodríguez-Barranco, Miguel; Huerta, Jose Maria; Gurrea, Aurelio Barricarte; Bradbury, Kathryn Erica; Trichopoulou, Antonia; Bamia, Christina; Orfanos, Philippos; Palli, Domenico; Pala, Valeria; Vineis, Paolo; Bueno-De-Mesquita, Bas; Ohlsson, Bodil; Harlid, Sophia; Van Guelpen, Bethany; Skeie, Guri; Weiderpass, Elisabete; Jenab, Mazda; Murphy, Neil; Riboli, Eilo; Gunter, Marc J.; Aleksandrova, Krasimira Jekova; Tzoulaki, Ioanna (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-03)
      <i>Objective</i> - To systematically identify and validate published colorectal cancer risk prediction models that do not require invasive testing in two large population-based prospective cohorts.<p><p> <i>Design</i> - Models were identified through an update of a published systematic review and validated in the European Prospective Investigation into Cancer and Nutrition (EPIC) and the UK ...
    • Consumption of dairy products and colorectal cancer in the European prospective investigation into cancer and nutrition (EPIC) 

      Murphy, Neil; Norat, Teresa; Ferrari, Pietro; Jenab, Mazda; Bueno-de-Mesquita, Bas; Skeie, Guri; Olsen, Anja; Tjønneland, Anne; Dahm, Christina C.; Overvad, Kim; Boutron-Ruault, Marie Christine; Clavel-Chapelon, Françoise; Nailler, Laura; Kaaks, Rudolf; Teucher, Birgit; Boeing, Heiner; Bergmann, Manuela M.; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Palli, Domenico; Pala, Valeria; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; Peeters, Petra H.M.; Dik, Vincent K.; Weiderpass, Elisabete; Lund, Eiliv; Garcia, José Ramon Quiros; Zamora-Ros, Raul; Pérez, Maria José Sánches; Dorronsoro, Miren; Navarro, Carmen; Ardanaz, Eva; Manjer, Jonas; Almquist, Martin; Johansson, Ingegerd; Palmqvist, Richard; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Crowe, Francesca L.; Fedirko, Veronika; Gunter, Mark J.; Riboli, Elio (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: Prospective studies have consistently reported lower colorectal cancer risks associated with higher intakes of total dairy products, total milk and dietary calcium. However, less is known about whether the inverse associations vary for individual dairy products with differing fat contents. Materials and Methods: In the European Prospective Investigation into Cancer and Nutrition (EPIC), ...
    • Consumption of ultra-processed foods associated with weight gain and obesity in adults: A multi-national cohort study 

      Cordova, Reynalda; Kliemann, Nathalie; Huybrechts, Inge; Rauber, Fernanda; Vamos, Eszter P.; Levy, Renata Bertazzi; Wagner, Karl-Heinz; Viallon, Vivian; Casagrande, Corinne; Nicolas, Geneviève; Dahm, Christina Catherine; Zhang, Jie; Halkjær, Jytte; Tjønneland, Anne; Boutron-Ruault, Marie-Chiristine; Mancini, Francesca Romana; Laouali, Nasser; Katzke, Verena; Srour, Bernard; Jannasch, Franziska; Schulze, Matthias B; Masala, Giovanna; Grioni, Sara; Panico, Salvatore; van der Schouw, Yvonne T; Derksen, Jeroen W.G.; Rylander, Charlotta; Skeie, Guri; Jakszyn, Paula; Rodríguez-Barranco, Miguel; Huerta, José María; Barricarte, Aurelio; Brunkwall, Louise; Ramne, Stina; Bodén, Stina; Perez-Cornago, Aurora; Heath, Alicia K; Vineis, Paolo; Weiderpass, Elisabete; Monteiro, Carlos Augusto; Gunter, Marc J; Millett, Christopher J.; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-26)
      Background - There is a worldwide shift towards increased consumption of ultra-processed foods (UPF) with concurrent rising prevalence of obesity. We examined the relationship between the consumption of UPF and weight gain and risk of obesity.<p> <p>Methods - This prospective cohort included 348 748 men and women aged 25–70 years. Participants were recruited between 1992 and 2000 from 9 European ...
    • Diet-wide association study of 92 foods and nutrients and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition study and the Netherlands Cohort Study 

      Heath, Alicia K.; Muller, David C.; van den Brandt, Piet A.; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Weiderpass, Elisabete; Boeing, Heiner; Ferrari, Pietro; Merritt, Melissa A.; Rostgaard-Hansen, Agnetha L.; Tjønneland, Anne; Overvad, Kim; Katzke, Verena; Srour, Bernard; Masala, Giovanna; Sacerdote, Carlotta; Ricceri, Fulvio; Pasanisi, Fabrizio; Bueno-de-Mesquita, Bas; Downward, George S.; Skeie, Guri; Sandanger, Torkjel M; Crous-Bou, Marta; Rodríguez-Barranco, Miguel; Amiano, Pilar; Huerta, José María; Ardanaz, Eva; Drake, Isabel; Johansson, Mikael; Johansson, Ingegerd; Key, Tim; Papadimitriou, Nikos; Riboli, Elio; Tzoulaki, Ioanna; Tsilidis, Konstantinos K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-13)
      It is unclear whether diet, and in particular certain foods or nutrients, are associated with lung cancer risk. We assessed associations of 92 dietary factors with lung cancer risk in 327 790 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cox regression yielded adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) per SD higher intake/day of ...
    • Dietary Fibre Intake and Risks of Cancers of the Colon and Rectum in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Murphy, Neil; Norat, Teresa; Ferrari, Pietro; Jenab, Mazda; Bueno-de-Mesquita, H. Bas; Skeie, Guri; Dahm, Christina C.; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie Christine; Racine, Antoine; Kaaks, Rudolf; Teucher, Birgit; Boeing, Heiner; Bergmann, Manuela M.; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Lagiou, Pagona; Palli, Domenico; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Siersema, Peter D.; van Duijnhoven, Fränzel J.B.; Peeters, Petra H M; Hjartåker, Anette; Engeset, Dagrun; Gonzalez, Carlos A.; Sánchez, Maria-José; Dorronsoro, Miren; Navarro, Camen; Ardanaz, Eva; Quirós, José R.; Sonestedt, Emily; Ericson, Ulrika; Nilsson, Lena; Palmqvist, Richard; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Crowe, Francesca L.; Fedirko, Veronika; Wark, Petra A.; Chuang, Shu-Chun; Riboli, Eilo (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Earlier analyses within the EPIC study showed that dietary fibre intake was inversely associated with colorectal cancer risk, but results from some large cohort studies do not support this finding. We explored whether the association remained after longer follow-up with a near threefold increase in colorectal cancer cases, and if the association varied by gender and tumour location. After a mean ...